Archives of Gastroenterology Research

Case Series Open Access

Risankizumab Demonstrates Clinical and Biochemical Effectiveness in Inflammatory Bowel Disease: A Retrospective Observational Study

Chamith H. Gunaratne , Tausif Hussain , Anas Hatab , Joseph Collum

To evaluate the real-world safety and effectiveness of risankizumab in patients with inflammatory bowel disease (IBD), using clinical outcomes and faecal calprotectin (FCP) as markers of response. A retrospective observational study was conducted at East Lancashire Hospitals NHS Trust. Patients with a confirmed diagnosis of IBD who were initiated on risankizumab were included. Clinical outcomes, FCP levels, and treatment tolerability were assessed. As FCP values were non-normally distributed (Shapiro–Wilk p < 0.05), the Wilcoxon signed-rank test was used to compare pre-and post-treatment values.

Arch Gastroenterol Res, 2026, Volume 7, Issue 1, p1-7 | DOI: 10.33696/Gastroenterology.7.074

Case Report Open Access

Pleomorphic Rhabdomyosarcoma of the Splenic Hilum in an Elderly Female with Prior Ovarian Cancer: A Rare Case Report

Paula Grisales , Steven D Trocha

Pleomorphic rhabdomyosarcoma (PRMS) is a rare and aggressive soft tissue sarcoma that typically occurs in the extremities of older adults. Involvement of the splenic hilum is extremely rare and has not been previously reported in the literature. We present the case of an 81-year-old female with a remote history of high-grade serous carcinoma of the ovary who presented with new-onset vaginal bleeding. Imaging revealed a mass in the left upper quadrant at the interface of the spleen and pancreatic tail.

Arch Gastroenterol Res, 2026, Volume 7, Issue 1, p8-12 | DOI: 10.33696/Gastroenterology.7.075

Original Research Open Access

Bile Duct Injury in the Laparoscopic Era: Clinical Spectrum, Optimal Management and Outcomes from Dual Tertiary Care Centres of North India

Wasif Mohammad Ali , Shivram Singh Yadav , Hazique Jameel , Ahmad Sadiq , Naimish N Mehta

Bile duct injury (BDI) is one of the most serious complications of cholecystectomy associated with substantial risk of morbidity and mortality. Although surgical techniques have evolved, bile duct injuries continue to occur with notable frequency. To evaluate the demographic profile, presentation, classification, management, and outcomes of patients with BDI following laparoscopic cholecystectomy.

Arch Gastroenterol Res, 2026, Volume 7, Issue 1, p13-23 | DOI: 10.33696/Gastroenterology.7.076