Archives of Clinical Ophthalmology

Commentary Open Access

Macular Microcirculation after Rhegmatogenous Retinal Detachment Repair Evaluated by OCT-Angiography

Evita Evangelia Christou, Maria Stefaniotou

In the process of rhegmatogenous retinal detachment (RRD), retinal homeostasis may be adversely affected with resultant modifications in retinal and choroidal tissue. Hypoxia and nutrient deprivation along with inflammation at the detached retina may lead to morphological and microvascularity alterations. These changes imply that the functional status of the macula may not be entirely restored despite anatomical repair.

Case Report Open Access

Uhthoff ’s Phenomenon as Presentation of COVID-19 Infection

Pieter Gouws, Alexander Gouws

This is the first reported case of COVID-19 associated optic neuritis (ON) presenting with classic Uhtoff’s phenomenon typically associated with multiple sclerosis (MS). Uhthoff phenomenon, also known as Uhthoff sign or syndrome, is a transient worsening of neurological function lasting less than 24 hours that can occur in multiple sclerosis patients due to increases in core body temperature.

Original Research Open Access

Repeatability of Scheimpflug Corneal Tomography in Patients with Keratoconus and Different Body Mass Indices

James S Lewis, Lize Angelo, Akilesh Gokul, Charles NJ McGhee, Mohammed Ziaei

To evaluate the repeatability of corneal tomographic parameters in keratoconus patients across different body mass index (BMI) categories. This prospective study was conducted at the University of Auckland, New Zealand, from June 2021 to June 2022. A total of 243 eyes from keratoconus patients aged 18-45 years were categorized into normal (BMI ≤24.9; n=55), overweight (BMI 25.0-29.9; n=58), and obese (BMI ≥30.0; n=130) groups. Patients underwent three consecutive scans using the Pentacam AXL.

Commentary Open Access

Focal Aggregates of Normal or Near Normal Uveal Melanocytes (FANNUMs) in the Choroid. A Practical Clinical Category of Small Ophthalmoscopically Evident Discrete Melanocytic Choroidal Lesions

James J. Augsburger

Multiple types of discrete melanocytic choroidal lesions are currently recognized, including benign choroidal nevi, choroidal malignant melanomas, patches of choroidal melanocytosis, and foci of choroidal melanocytes stimulated paraneoplastically by a systemic nonmelanoma malignant neoplasm.

Editorial Open Access

Mega-Dose Dietary Riboflavin in Treatment in Keratoconus, Post-Refractive Cornea Ectasia and Migraine. Has Its Time Arrived?

John Steven Jarstad

Recently, several studies and investigators have shown the beneficial effects of high dose dietary riboflavin (vitamin B2) in the treatment of keratoconus, post-refractive (LASIK, PRK & Radial Keratotomy) ectasia (with sunlight exposure) and patients treated with our own protocol (NIH Clinical Study – www.clinicaltrials.gov - # NCT 03095235) discovered significant relief for intractable migraine headaches and/or ophthalmic migraine (classic migraine visual symptoms without headache).