Exosomes are membranous vesicles ranging in size from 30–100 nm in diameter. They are secreted from multiple cell types into the body fluids through exocytosis, a process commonly used for receptor discharge and intercellular communications.Arch Cancer Biol Ther, 2021, Volume 2, Issue 2, p29-34 | DOI: 10.33696/cancerbiology.2.021
This commentary refers to our published article, as highlighted in this article most common gene causing breast cancer in the population living in the United Arab Emirates is BRCA2 followed by BRCA1. This is the first publication discussing about clinical and pathological features of breast cancer in woman with a positive genetic mutation in the United Arab Emirates.Arch Cancer Biol Ther, 2021, Volume 2, Issue 2, p35-36 | DOI: 10.33696/cancerbiology.2.022
Primary small cell neuroendocrine carcinoma of the urinary bladder is a rare histological type shows poor differentiation and behaves in a highly aggressive manner. It accounts to 0.3- 0.7% of all bladder tumors [1,2]. Neuroendocrine carcinomas predominantly occur in respiratory and gastrointestinal tract and very rarely in the urinary bladder.Arch Cancer Biol Ther, 2021, Volume 2, Issue 2, p37-39 | DOI: 10.33696/cancerbiology.2.023
Molecular Biology for BCR-ABL1 Quantification for Chronic Myeloid Leukemia Monitorization and Evaluation
Chronic Myeloid Leukemia (CML) is a clonal disorder originated by a pluripotent hematopoietic stem cell, which presents the translocation t(9;22) (q34;q11) in 90% of the cases.Arch Cancer Biol Ther, 2021, Volume 2, Issue 2, p40-42 | DOI: 10.33696/cancerbiology.2.024
The human body is constituted by more than 200 committed cell types , all of which derive from the zygote, a single totipotent cell that divides and differentiates into all the cells of an organism throughout its development. Out of this diversity, we focus our interest here on the epithelial and the mesenchymal cells.Arch Cancer Biol Ther, 2021, Volume 2, Issue 2, p43-49 | DOI: 10.33696/cancerbiology.2.025
Tyrosine kinase-type cell surface receptor HER2- targeted therapies have dramatically improved breast cancer patients’ outcome compared to conventional chemotherapies. In the clinic, HER2 monoclonal antibody trastuzumab with chemotherapy represent the gold standard treatment of HER2-positive breast cancer.Arch Cancer Biol Ther, 2021, Volume 2, Issue 2, p50-53 | DOI: 10.33696/cancerbiology.2.026
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