Archives of Cancer Biology and Therapy
Exosome to Promote Cancer Progression via Its Bioactive Cargoes
Exosomes are membranous vesicles ranging in size from 30–100 nm in diameter. They are secreted from multiple cell types into the body fluids through exocytosis, a process commonly used for receptor discharge and intercellular communications.Arch Cancer Biol Ther, 2021, Volume 2, Issue 2, p29-34 | DOI: 10.33696/cancerbiology.2.021
The Challenge of Cognitive Dissonance in the Delivery of Precision Medicine in Veterinary Oncology
The use of molecular and genomic analysis of a cancer as a means to define a patient-specific treatment is interchangeably referred to as Precision Medicine, Personalized Medicine, or Genomically-directed medicine (herein, collectively PMED).Arch Cancer Biol Ther, 2020, Volume 1, Issue 2, p37-41 | DOI: 10.33696/cancerbiology.1.008
Synthetic Lethal Drug Combinations Targeting Proteasome and Histone Deacetylase Inhibitors in TP53-Mutated Cancers
Tumors harboring mutations in certain oncogenes are often dependent on activation of certain pathways which becomes essential for the survival of the cancer cells. This condition is formally known as synthetic lethality, a state when simultaneous loss of two genes is lethal to a cancer cell, while the loss of the individual genes is not.Arch Cancer Biol Ther, 2020, Volume 1, Issue 2, p42-47 | DOI: 10.33696/cancerbiology.1.009
Lessons Learnt from COVID-19: How Can We Prepare for Another Pandemic?
Five months into the COVID-19 pandemic, the U.S. death toll from the virus has now surpassed 100,000 people. Many more cases remain nationwide, while an unknown number of patients currently harbor the virus asymptomatically. While health officials are now optimistic regarding the decline in prevalence and number of deaths due to COVID-19 and the possibility of a vaccine by the fall, we cannot lose sight of the bigger picture: the next pandemic.Arch Cancer Biol Ther, 2020, Volume 1, Issue 1, p22-24 | DOI: 10.33696/cancerbiology.1.005
Impact of Cisplatin Dosing Regimens on Mammary Tumor Growth in an Animal Model
In a recent paper, we introduced a variant of the classical Simeoni tumor growth model, and illustrated its value in assessing tumor growth in a reproducible mouse model for mammary tumors. Our modification consisted of incorporating delay differential equations in the mathematical formulation of the Simeoni model, to represent the delay in drug action often observed under chemotherapeutic or immunotherapeutic regimens.Arch Cancer Biol Ther, 2020, Volume 1, Issue 1, p18-21 | DOI: 10.33696/cancerbiology.1.004
Uniportal VATS Lobectomy for Lung Cancer: Feasibility and Cost Effectiveness in a Single Center Experience
In last decades, video-assisted thoracic surgery (VATS) together with robotic-assisted thoracic surgery (RATS) can be considered the biggest innovation in thoracic surgery. This approach drastically changed the way of performing surgical operations, improving patient’s outcome undergoing thoracic surgery.Arch Cancer Biol Ther, 2020, Volume 1, Issue 1, p1-10 | DOI: 10.33696/cancerbiology.1.001
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