Health intelligence on the frequency of cardiovascular disease (CVD) and its risk factors identifies targets and populations for preventative strategies and allows evaluation of health outcomes, behaviors and interventions in populations and health care settings.

Sialyllactose, known to be abundant in human breast milk, has anti-inflammatory properties, but its preventive effect on osteoarthritis remain unclear. Here, we demonstrated the efficacy of 3’ sialyllactose (3’ SL) and 6’ sialyllactose (6’ SL) in preventing osteoarthritis in Yucatan mini-pigs. Twelve female Yucatan mini-pigs were administered 0, 200, 400 mg 3’ SL or a combination of 200 mg 3’ SL + 200 mg 6’ SL for 12 weeks (4weeks before and 8 weeks after surgery); then, osteoarthritis was induced in the left knee by anterior cruciate ligament transection surgery. Kinematic variables were used to quantify gait analysis on the treadmill, and the degree of osteoarthritis was analyzed in the femur and tibia cartilage

RSA is a worldwide treatment to manage pain and improve shoulder function in patients with advanced gleno-humeral osteoarthritis. The main efforts of researchers were directed to address glenoid replacement, using devices that would preserve glenoid bone stock and ensure prosthesis stability.