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Journal of Cellular Immunology

ISSN: 2689-2812

Review Article Open Access
Volume 1 | Issue 2 | DOI: https://doi.org/10.33696/immunology.1.007

TNFAIP8: Inflammation, Immunity and Human Diseases

Suryakant Niture1, John Moore1, Deepak Kumar1,*
  • 1Julius L. Chambers Biomedical Biotechnology Research Institute, North Carolina Central University Durham, NC 27707, USA
+ Affiliations - Affiliations

Corresponding Author

Deepak Kumar, dkumar@nccu.edu

Received Date: September 21, 2019

Accepted Date: October 07, 2019

Citation:

Niture S, Moore J, Kumar D. TNFAIP8: Inflammation, Immunity and Human Diseases. J Cell Immunol. 2019; 1(2):29-34.


Copyright: © 2019 Niture S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8 /TIPE) family proteins are known to be involved in maintaining immune homeostasis. The TIPE family contains four members: tumor necrosis factor-α-induced protein 8 (TNFAIP8), TNFAIP8 like 1 (TIPE1), TNFAIP8 like 2 (TIPE2), and TNFAIP8 like 3 (TIPE3). Here we review the latest roles and associations of a founding member of TIPE family protein - TNFAIP8 in cellular function/signaling, inflammation, and immunity related human diseases.

Keywords

TNFAIP8, Inflammation, Immunity

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