Neurofibromatosistype 1 (NF1) is a complex, multisystem, autosomal dominant disease that has widespread effects on ectodermal and mesodermal tissues. The progress in genetic studies and in cosmetics and aesthetic and reconstructive surgery have ameliorated the quality of life in women with NF1. In this review we update the most relevant data on gynecological life and reproductive issues in women with NF1.

Neurofibromatosis type 1, Pregnancy, Rare disease, Neurofibroma degeneration