Mini Review Open Access
Volume 2 | Issue 3 | DOI: https://doi.org/10.33696/Gynaecology.2.023

Reproductive Issues in Neurofibromatosis Type 1: An Update

  • 1Ospedale San Marco, UOC Ostetricia e Ginecologia e PS, Catania, Italy
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Corresponding Author

Franco Pepe, franco_pepe@libero.it

Received Date: November 22, 2021

Accepted Date: December 16, 2021


Neurofibromatosistype 1 (NF1) is a complex, multisystem, autosomal dominant disease that has widespread effects on ectodermal and mesodermal tissues. The progress in genetic studies and in cosmetics and aesthetic and reconstructive surgery have ameliorated the quality of life in women with NF1. In this review we update the most relevant data on gynecological life and reproductive issues in women with NF1.


Neurofibromatosis type 1, Pregnancy, Rare disease, Neurofibroma degeneration

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