Commentary Open Access
Volume 2 | Issue 2 | DOI: https://doi.org/10.33696/cancerbiology.2.022
Genetic Predisposition of Breast Cancer in the United Arab Emirates
Ajda Altino1,*, Ahmed Abdel-Aziz2, Mouza Al Ameri3
- 1ACGME-I Accredited General Surgery Residency Program, Tawam Hospital, Abu Dhabi, United Arab Emirates
- 2Department of Anesthesia, Tawam Hospital, Al Ain, Abu Dhabi, United Arab Emirates
- 3Department of Breast Surgery, Tawam Hospital, Al Ain, Abu Dhabi, United Arab Emirates
Corresponding Author
Ajda Altinoz, ajtinoz@seha.ae
Received Date: May 18, 2021
Accepted Date: June 07, 2021
Altinoz A, Abdel-Aziz A, Ameri MA. Genetic Predisposition of Breast Cancer in the United Arab Emirates. Arch Cancer Biol Ther. 2021; 2(2): 35-36.
Copyright: © 2021 Altinoz A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Recommended Articles
Chimeric Antigen Receptor CAR NK Cells Emerging Immunotherapy for the Treatment of Cancer
Although NK cells are recognized as effector lymphocytes of the innate immune system, they also regulate the adaptive immune response by releasing inflammatory cytokines and developing immunological memory. Unlike other lymphocytes such as T or B cells, NK cells do not express rearrangeable, antigen-specific receptors.
Emerging Role of TRPML1 Mucolipin Endolysosomal Channel in Cancer
The transient receptor potential mucolipin 1 (TRPML1) is an endolysosomal channel belonging to the TRP family. Clinically, mutations of TRPML1 have been responsible for a severe lysosomal storage disorder called mucolipidosis type IV.
Circulating Cell-Free RNA: A New Perspective for Endometrial Cancer
In order to implement the knowledge of cancer to monitor its evolution and setting, in the last decade, new minimally invasive and repeatable samples collection have been developed such as liquid biopsy. Cancer biomarkers originating from tumors can represent the molecular status of the tumor or its metastases which release them directly into body fluids or indirectly due to disruption of tumor/metastatic tissue. These biomarkers are detectable in liquid biopsy.
Sentinel Lymph Node Biopsy after Neoadjuvant Chemotherapy for Breast Cancer
Breast cancer is the second most common cancer worldwide, affecting nearly one in eight women. Accurate cancer staging is essential for determining the patient’s prognosis and for choosing the appropriate treatment. The staging system most often used is the American Joint Committee on Cancer (AJCC) TNM system, where T refers to the size of the tumor, N refers to spread of the primary cancer to nearby lymph nodes, and M refers to the spread of metastasis to distant sites in the body.
Platelet Hyperactivity and Dysfunction in Diabetes and Cancer
However, the entire coagulation cascade is dysfunctional, in progressed chronic diabetes and cancer patients. Platelets (PLTs) in type 2 diabetic (DT2) involved in Thrombosis and Haemostasis (T&H) of individuals adhere to vascular endothelium and aggregate more voluntarily than those in healthy individuals, as are abnormalities in the microvascular and macrovascular circulations. However it is already known that the circulating PLTs are essential for T&H, inflammation growth factors delivery, regeneration; and knowledge of their function is fundamental to understanding the pathophysiology of vascular disease in diabetes and cancer-related diseases.