Choosing an individual medication for a particular patient is one of the most important clinical decisions in family medicine (FM). Prescription of drugs is currently the main tool of FM and that’s the main source of prescription of drugs. The drugs are used by general practitioners (GPs) to manage a wide range of health problems that are addressed at this level of medical care have tangible results. But should the drug be the GP’s main therapeutic resource? Drugs arrive to serve the purposes of the GP, but finally, the GP redefines its own goals according to the drugs. Prescription rates have increased and polypharmacy is very frequent, a new doctorpatient relationship has appeared: a “patient-drug relationship” where the GP is excluded, there is an increase in yatrogenesis because of high rate of adverse drug reactions and drug-drug-interactions, and the importance of the non-pharmacological aspects of the medication is completely forgotten. In the matter of drugs on FM it is necessary to take into account the opposition and relationship between “the content and the form.” The “content” is not in the drugs; it is in conceptual foundations of FM and the GP must not forget the crucial elements on which his/her work is based: the use of a special clinical interview, continuity of care, knowledge of the context for the diagnosis and treatment, the wise use of drugs and technologies, and a permanent ability to critically reflect on the situation presented in the consultation.

Drug utilization, Prescription drugs, Pharmaceutical treatment, Family practice, General practice, Polypharmacy, Drug interactions, Inappropriate prescribing, Prescribing influences, Physician-patient relations, Framework