Short Communication Open Access
Volume 2 | Issue 3 | DOI: https://doi.org/10.33696/haematology.2.034
Atezolizumab Monotherapy as First-line Treatment in Patients with Advanced BRAFV600 Wild-type Melanoma
Juliano C. Coelho1,2,*, Taiane F. Rebelatto1,2, Rodrigo R. Pereira1,2,3, Pedro E. R. Liedke1,2,3, Andrea B. Zanon1, Sergio J. Azevedo1,2,3
- 1Unidade de Pesquisa Clínica em Oncologia, Porto Alegre, Brazil
- 2Oncology Department, Oncoclinicas Group, Porto Alegre, Brazil
- 3Department of Oncology, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil
Corresponding Author
Juliano C. Coelho, juliano.oncologia@gmail.com
Received Date: May 20, 2021
Accepted Date: June 28, 2021
Coelho JC, Rebelatto TF, Pereira RR, Liedke PER, Zanon AB, Azevedo SJ. Atezolizumab Monotherapy as First-line Treatment in Patients with Advanced BRAFV600 Wild-type Melanoma. J Clin Haematol. 2021; 2(3): 95-97.
Copyright: © 2021 Coelho JC, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Recommended Articles
Chimeric Antigen Receptor CAR NK Cells Emerging Immunotherapy for the Treatment of Cancer
Although NK cells are recognized as effector lymphocytes of the innate immune system, they also regulate the adaptive immune response by releasing inflammatory cytokines and developing immunological memory. Unlike other lymphocytes such as T or B cells, NK cells do not express rearrangeable, antigen-specific receptors.
Deubiquitinase as Potential Targets for Cancer Immunotherapy
During the last few decades, immunotherapy is considered to be an important approach to help our immune system to fight various kinds of diseases, such as tumor. Sometimes, it works very well for some types of cancers, for example: bladder cancer, colorectal cancer, breast cancer and lymphoma.
Role of the Gut Microbiome in the Modulation of Cancer Immunotherapy Response
The gut microbiome or gut flora is a vast community of microorganisms such as bacteria, viruses, protozoa, and fungi that inhabit the digestive tract of the human and other animals [1,2]. In the human body, bacterial species colonize into the oral cavity, skin, vagina, and placenta, however, the largest population of microorganisms resides in the intestine.
Acute Abdomen due to Perforation of Small Bowel Malignant Melanoma Metastasis
Primary tumors of the small bowel are a rare condition, accounting for 2 to 3% of gastrointestinal tumors. Malignant melanoma is the most common metastatic tumor found in the gastrointestinal tract [1]. It can be localized in different sites, from the oral cavity to the anus. It can also be present as a primary lesion.
CTLA-4 and PD-L1 or PD-1 Pathways: Immune Checkpoint Inhibitors and Cancer Immunotherapy
The immune system developed certain checks and balance to control or inhibit the reactivity against normal cells of the body. Uncontrolled immune responses to the non-self entities such as bacteria, viruses, parasites, or mutated self-antigens can cause an inflammatory reaction and autoimmune diseases.