Archives of Molecular Biology and Genetics

Review Article Open Access

Embracing Neurodiversity: The Critical Role of Awareness And  Acceptance in Autism Spectrum Disorders

Aayushi Gupta , Nadir Aman

This review provides a comprehensive overview of autism spectrum disorder (ASD), focusing on its early signs, clinical presentation, etiology, screening and diagnosis, therapeutic interventions, and the critical role of family support. ASD characterized by a range of challenges in social communication, behavior, and sensory processing, with symptoms manifesting in early childhood. While the exact causes remain unclear, a combination of genetic and environmental factors believed to contribute to its development.

Arch Mol Biol Genet, 2025, Volume 4, Issue 1, p1-8 | DOI: 10.33696/genetics.4.019

Commentary Open Access

Regeneration: Evolutionary Changes Explain the Different Distribution among Animals and Loss in Terrestrial Species

Lorenzo Alibardi

This manuscript summarizes recent hypotheses to explain the distribution of regenerative abilities among animals. The hypothesis is based on evolutionary considerations pointing out that while organ or even body regeneration is present in marine animals, limited regeneration or no regeneration is manifested in terrestrial animals. This loss derives from the terrestrial conditions for life, primarily including shortage of water, high UV and ROS exposition. 

Arch Mol Biol Genet, 2025, Volume 4, Issue 1, p9-12 | DOI: 10.33696/genetics.4.020

Review Article Open Access

Chromosome Dynamics in Cancer: From Mitotic Errors to Genomic Catastrophes and Therapeutic Vulnerabilities

Jagadeeswara Rao Bommi

Chromosome dynamics—including segregation fidelity, nuclear architecture, micronuclei formation, and chromothripsis—plays a central role in cancer evolution, intra-tumoral heterogeneity, and therapy resistance. Defective mitosis and subsequent chromosomal mis-segregation rapidly generate aneuploidy and structural rearrangements, accelerating tumor adaptation under selective pressures.

Arch Mol Biol Genet, 2025, Volume 4, Issue 1, p13-17 | DOI: 10.33696/genetics.4.021

Editorial Open Access

Usage of Artificial Intelligence in Biomedical Publishing

Ralf Weiskirchen , Amedeo Lonardo

Artificial intelligence (AI) has become an essential tool in modern biomedical research. However, its increasing role in manuscript preparation raises urgent ethical and practical questions. This editorial discusses the main AI modalities currently influencing molecular biology and genetics machine learning, deep learning, natural language processing, and large language models.

Arch Mol Biol Genet, 2025, Volume 4, Issue 1, p18-20 | DOI: 10.33696/genetics.4.022