Archives of Molecular Biology and Genetics

Short Communication Open Access

Actors of ROS Homeostasis in Stigmatic Cells Essential for Plant Reproduction

Chie Kodera , Isabelle Fobis-Loisy

Reactive oxygen species (ROS) play important roles during development and responses to external stimuli. In Brassicaceae, the stigma epidermis accumulates a large amount of ROS. Moreover, regulating the stigmatic ROS status is crucial for Self-incompatibility (SI) mechanisms, to ensure self-pollen rejection while promoting compatible pollen. Here, scanning our transcriptomic data in light of recent advances in the Brassicaceae SI system, we identified Class III peroxidases that are highly expressed in mature stigma and might regulate stigma ROS homeostasis.

Review Article Open Access

Impact of Sleep on Autophagy and Neurodegenerative Disease: Sleeping Your Mind Clear

Samuel Deutsch , Bilal R. Malik

Sleep is an evolutionarily conserved phenomenon which has survived tremendous evolutionary pressures. Its disruption has deleterious implications for human health. The importance of sleep is illustrated by the fact that sleep deprivation in many animals leads to death. While sleep is tightly regulated by a combination of intrinsic and extrinsic factors it becomes progressively disrupted in old age and in neurodegenerative diseases including Alzheimer’s disease (AD), frontotemporal dementia (FTD), Parkinson’s disease (PD) and Huntington’s disease (HD). 

Review Article Open Access

SARS-CoV-2 Mutations, Diagnosis and Their Concern

Yakup Artik , Nevra Pelin Cesur , Nelisa Türkoğlu Laçin

The first case is described in Wuhan city of China in December 2019 and the disease (COVID-19) continues to pose threat to global health all over the world affecting more than approximately 476 million confirmed cases and 6 million deaths. Reliable and effective methods are taken a critical role such as real-time reverse transcriptase (RT)-PCR test as a gold standard method, serological tests, and reverse transcriptase loopmediated isothermal amplification (RT-LAMP) method is chosen firstly. 

Commentary Open Access

Commentary on "Type II Toxin-antitoxin Systems Have a Peculiar Localization in Escherichia Coli Cells"

Alexander Mager , Hanna Engelberg-Kulka

Bacterial Toxin-Antitoxin (TA) modules were extensively studied. They are located on extra chromosomal genetic elements as well as on bacterial chromosomes. They carry two genes. One encoding for the toxin, and the other for the antitoxin. The toxin is a stable protein, while the antitoxin is either RNA or a labile protein. They are divided into six groups, among them group II is the most studied. 

Review Article Open Access

Risk Management Implemented by Turkey during the COVID-19 Pandemic Disaster

Nehir Varol , Yakup Artik , Timur Gültekin

The coronavirus (COVID-19) outbreak occurred in China and spread to the whole world in a short period of time. The WHO (World Health Organization) named the viral disease as COVID-19 (Novel Coronavirus, SARS-CoV-2) on February 11, 2020.