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Archives of Molecular Biology and Genetics
ISSN: 2831-6754
Gut Microbiota Metabolite Trimethylamine N-oxide Reduced Pancreatic β Cell Calcium Transients and Function
Pancreatic β cell dysfunction is an important cause of type 2 diabetes (T2D). Previous studies show trimethylamine N-oxide (TMAO), a gut microbiota-related metabolite, promotes cardiovascular disease and insulin resistance. However, the effect and mechanism of TMAO at pathological concentrations on β cell function remain unknown. The recently published work demonstrates TMAO reduces pancreatic β cell function and glucose homeostasis.
Arch Mol Biol Genet, 2024, Volume 3, Issue 1, p1-4 | DOI: 10.33696/genetics.3.014Epigenomics of Adaptive Plasticity of Rice Under Changing Climatic Conditions Grown by Direct-sowing as well as Transplanting
The common practice of cultivating rice through transplanting requires considerably higher amount of water, which poses several challenges, particularly in the present era of global climate change and decreasing availability of water. The direct-sown rice (DSR) presents a promising/resource-saving alternative for cultivation of rice in the current scenario of changing climatic conditions. While some local cultivars are well-adapted for DSR, there has been limited success in breeding for DSR varieties.
Arch Mol Biol Genet, 2024, Volume 3, Issue 1, p5-19 | DOI: 10.33696/genetics.3.015Scientific Archives is a global publisher initiated with the mission of ensuring equal opportunity for accessing science to research community all over the world. Spreading research findings with great relevance to all channels without any barrier is our goal. We want to overcome the challenges of Open Access with ensured quality and transparency.