Pediatrics & Clinical Pharmacology
Wroclaw Medical University
Dr. Joseph Prandota received his Doctor of Medical Sciences degree (1970) and PhD degree (1980) from Wroclaw Medical University, Poland. He worked as Assistant/Adjunct in Department of Pharmacology (1966-1975), Department of Pediatric Nephrology (1975-1977), the Associate Professor, Full Professor and Chief in Department of Pediatrics, J. Korczak Memorial Children’s Hospital in Wroclaw (1978-2002), and then in the Faculty of Dentistry, and as the Chair and Head of Department of Social Pediatrics, Faculty of Health Sciences, Wroclaw Medical University (2002-2011). He received the Senior Fulbright-Hays Program award and worked in Department of Pediatrics, Emory University School of Medicine, Atlanta, GA (1973-175; director Dr. Albert W. Pruitt); obtained fellowship in Department of Pharmacology, Creteil, Paris XII, France (1977/1978; chairman Dr. Jean-Paul Tillement); was awarded The Kosciuszko Foundation Fellowship (twice) working in Department of Pediatrics, LSU in Shreveport, LA (1986); director Dr. John T. Wilson; and was a Visiting Professor in Department of Pediatrics and Pediatric Nephrology, School of Medicine, Hannover, Germany (September 1993; Chairman Dr. Johannes Brodehl). He published 65 peer-reviewed papers as the only or first author, and solved several important scientific/clinical puzzles, such as for example: the peculiar disposition of drugs in cystic fibrosis patients, the dangerous diuretic tienilic acid-coumarin derivatives interaction, the aquarium fish food proteins as the triggering agents in development of autoimmune hepatitis, the possible accumulation of cimetidine after multiple oral doses, the need for calculation of plasma elimination half-life of drugs only after reaching steady-state concentration, and an important role of viral infections in inhibition of xenobiotic-metabolizing enzymes leading to development of autoimmune hepatitis. Dr. Prandota demonstrated that T. gondii may cause different types of recurrent headaches (Am J Ther, 2007,14,63). He is an Editor of more than 50 scientific journals including World J Clin Pediatrics (China), Int J Neurology Res (Hong Kong), Archives of Clinical Hypertension (India), Global Journal of Gastroenterology & Hepatology (UK), and The Open Neurology Journal (USA). Recently, Dr Prandota et al found the increased seroprevalence of chronic toxoplasmosis in autistic children [Int J Neurol Res, 2015,1(3),102], and suggested that T. gondii may be responsible for the development of atherosclerosis (J Cardiol Ther, 2017,4(2).611).
Latent chronic T. gondii infection and its participation in the development of molecular pathomechanisms of headaches, several neurodegenerative, and autoimmune diseases, including autism, inflammatory bowel disease, Lesniowski-Crohn disease, cryptogenic liver disease, steatohepatitis, diabetes mellitus, atherosclerosis, idiopathic intracranial hypertension, and proteinuria
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