Shrestha+Ghosh | Scientific Archives

AUTHOR INFO

Shrestha Ghosh

Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA

Articles List

A Novel Guardian of Telomeres: RIOK2 Regulates Telomerase Activity Through TRiC and Dyskerin Complexes

Telomeres are repetitive DNA sequences located at chromosomal ends that are crucial for maintaining genomic stability. Telomere lengths are tightly regulated under physiological conditions, disruption of which results in telomere shortening that ultimately leads to telomere biology disorders, such as Dyskeratosis congenita (DC), bone marrow failure syndromes, and Idiopathic Pulmonary Fibrosis (IPF), amongst others. Progressive telomere shortening is also a well-recognized feature of aging.

J Cell Immunol, 2025, Volume 7, Issue 1, p1-8 | DOI: 10.33696/immunology.7.216

Co Authors

Merve Akyol Harvard Medical School, Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA View Profile

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