Elucidating how normal aging increases vulnerability to neurodegeneration remains a major gap in our understanding of disease risk and progression. The dorsal striatum serves as the primary input nucleus of the basal ganglia and is a key region implicated in multiple neurodegenerative diseases (NDDs). In Colon et al. 2025, we examined the impact of normal aging on neuroinflammatory signaling and perineuronal net (PNN) homeostasis within the dorsal striatum.
Alejandro Gamboa
Georgetown University School of Medicine, Department of Neuroscience, Georgetown University School of Medicine, Washington, DC, USA
View Profile
Scott Litwiler
Georgetown University School of Medicine, Department of Neuroscience, Georgetown University School of Medicine, Washington, DC, USA
View Profile
Zachary A Colon
Georgetown University School of Medicine, Interdisciplinary Program in Neuroscience, Georgetown University School of Medicine, Washington, DC, USA
View Profile