Mini Review Open Access
Volume 2 | Issue 2 | DOI: https://doi.org/10.33696/AIDS.2.010

Early Insights into COVID-19 in Persons Living with HIV and Cardiovascular Manifestations

  • 1Department of Medicine, University of Miami Miller School of Medicine/Jackson Memorial Hospital, Miami, Florida, USA
  • 2Behavioral Medicine Research Center, University of Miami, Miami, Florida, USA
  • 3Department of Psychology, University of Miami, Coral Gables, Florida, USA
  • 4Division of Endocrinology, Diabetes and Metabolism, Miller School of Medicine, University of Miami, Miami, Florida, USA
  • 5Department of Medicine, Division of Infectious Diseases, University of Miami Miller School of Medicine, Miami, Florida, USA
  • 6Department of Medicine, Division of Cardiovascular Disease, University of Miami Miller School of Medicine, Miami, Florida, USA
+ Affiliations - Affiliations

Corresponding Author

Claudia Martinez, cmartinez5@med.miami.edu

Received Date: August 08, 2020

Accepted Date: October 07, 2020


Persons living with HIV-1 (PLHIV) are at increased risk of cardiovascular complications in part due to the persistent inflammatory state despite viral suppression. SARS-CoV-2, the virus causing COVID-19, was declared a pandemic virus in March 2020, and caused over 30 million cases and 900,000 deaths worldwide to date. Individuals with COVID-19 are manifesting acute cardiovascular complications because of the inflammatory response associated with SARS-CoV-2 infection. It is not yet known whether having COVID-19 in the context of ongoing HIV-1 infection results in worse cardiovascular complications than in PLHIV who have not had COVID-19 infection. In this review, the potential for exacerbated cardiovascular manifestations in persons coinfected with HIV-1 and COVID-19 is considered.

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