Journal of Clinical Haematology

Original Research Open Access

HiDAC Consolidation Cycles May Impede Stem Cell Transplant Planning for High-Risk Acute Myeloid Leukemia Patients

Michael Stokes , Mohammad Mian , Anvay Shah , Yazmin Reategui-Almonacid , Isabela Pavkov , Jorge Cortes , Anand Jillella , Amany Keruakous , Carolina Hana , Vamsi Kota

Introduction: For patients with high-risk acute myeloid leukemia (AML), defined by certain cytogenetic (CG) and molecular genetic features, hematopoietic stem cell transplantation (HSCT) remains the only curative therapy. The logistics of proceeding to transplant might necessitate consolidation chemotherapy involving high dose cytarabine (HiDAC). 

J Clin Haematol, 2026, Volume 7, Issue 1, p1-12 | DOI: 10.33696/haematology.7.073

Review Article Open Access

Bispecific Antibodies and CAR-T cell Therapy in Multiple Myeloma

Margaret Locke , Amanda Lee , Maria J Nieto

Triple class exposed patients with multiple myeloma (MM) represent an unmet need with outcomes remaining poor with those with relapsed/refractory multiple myeloma (RRMM) having a mere 29.8% overall response rate and 12.4-month median overall survival. We explore emerging strategies focusing on bispecific antibodies and CAR-T cell therapies for treatment of refractory myeloma. 

J Clin Haematol, 2026, Volume 7, Issue 1, p13-18 | DOI: 10.33696/haematology.7.074

Editorial Open Access

Hematology and Blood Transfusion: An Indispensable Pillar of Medical Laboratory Science

Aloy-Amadi Oluchi Chinwe

Hematology and Blood Transfusion constitute one of the most distinctive and indispensable units within Medical Laboratory Science, underpinning a wide spectrum of clinical decision-making and lifesaving interventions. Discipline occupies a unique position in healthcare delivery by directly linking laboratory diagnostics with patient prognosis, therapeutic monitoring, and emergency management. Without robust hematology and transfusion services, modern clinical practice would be fundamentally compromised.

J Clin Haematol, 2026, Volume 7, Issue 1, p19-20 | DOI: 10.33696/haematology.7.075