Journal of Cellular Signaling

Yongxin Zhang

Department of Internal Medicine

ZYX Biotech Company

USA

Academic Editor

Biography

Dr. Yongxin Zhang is a General Manager (CEO) in Zyxell Inc, 1452 Halsey Way, Suite 100-1, Carrollton, TX 75007, USA. He worked as Director of Research and Senior Scientist in Regenetech Inc. Houston, USA (2006-2008). During 1992-1996, he worked as CEO, Senior Scientist and Physician-in-Chief in Beijing Hui-Jin Bio-Tech Institute, ZYX Biotech Ltd., Beijing, China. From 1989 to 1992, he was an Attending Physician and Research Associate in Eighth Department of Internal Medicine, BMCG Hospital, China. In 1983, Dr. Zhang completed his MD (Bachelor of Medicine) in Beijing Medical College, Beijing, China. During 1989, he graduated with Ph.D., from Beijing Medical University, Beijing, China. Later in 2004, he finished Postdoc training from Baylor College of Medicine, USA. Dr. Zhang has invented ZYX Bioreactor, which has great advantages in expansion of immunocytes and hepatopoiethic stem cells over other systems. He is an active Editorial Board member and reviewer in many international journals and he also done more than 30 publications as a corresponding author in peer-reviewed journals. Dr. Zhang received several awards and honors from various academies. Dr. Zhang’s research interests include Immunology of cancer and infectious diseases; Development and evaluation of new vaccines; Effects of apoptosis on immune system; Impact of aging on immunity; IgA and mucosal immunology; Studies on cell (including stem cells), tissue and organ transplantation, graft against host, immunosuppression as well as immunotolerance in cell transplantation; Molecular mechanism of the tissue construction and the “self-renewal” maintenance in expanding stem cells; Stem cell and immunocyte expansion; Bio-reactor development; Preparation, purification and conjugation of monoclonal antibodies; Development and commercialization of new immunoassays and molecular biologic assays (including rapid HLA typing assay) for clinical application; Study of immunological and molecular biologic mechanisms of acute and chronic infection using immunological, molecular biologic, microbiologic, pathologic, epidemic and statistical methods; Study of structure and function of genes and proteins with the technique of gene cloning and expression as well as Crispr/Cas9 gene edition, gene knockout and gene transfection; Diagnosis, treatment and prevention of cancer, infectious diseases, and liver diseases; Animal models: Virus infection mouse model and surgically-induced liver failure rat model.

Research Interest

Dr. Zhang’s research interests include Immunology of cancer and infectious diseases; Development and evaluation of new vaccines; Effects of apoptosis on immune system; Impact of aging on immunity; IgA and mucosal immunology; Studies on cell (including stem cells), tissue and organ transplantation, graft against host, immunosuppression as well as immunotolerance in cell transplantation; Molecular mechanism of the tissue construction and the “self-renewal” maintenance in expanding stem cells; Stem cell and immunocyte expansion; Bio-reactor development; Preparation, purification and conjugation of monoclonal antibodies; Development and commercialization of new immunoassays and molecular biologic assays (including rapid HLA typing assay) for clinical application; Study of immunological and molecular biologic mechanisms of acute and chronic infection using immunological, molecular biologic, microbiologic, pathologic, epidemic and statistical methods; Study of structure and function of genes and proteins with the technique of gene cloning and expression as well as Crispr/Cas9 gene edition, gene knockout and gene transfection; Diagnosis, treatment and prevention of cancer, infectious diseases, and liver diseases; Animal models: Virus infection mouse model and surgically-induced liver failure rat model.