Archives of Nephrology and Renal Studies

Luping Huang

Department of Medicine

Baylor College of Medicine

USA

Academic Editor

Biography

Dr. Luping Huang is currently working as an assistant professor in the Department of Neuroscience, at Wight State University, USA. She is also an adjunct assistant professor in the Department of Medicine at Baylor College of Medicine, USA. She has received her MD from Southeast University, School of Medicine, Nanjing, P.R. China in the year 1985. Later, she has received her Ph.D in  Medicine from Tokushima University School of Medicine, Tokushima, Japan. She worked as a Postdoc at Tulane University School of Medicine, New Orleans, LA, USA from 2001-2005 and at Baylor College of Medicine, Houston, TX, USA from 2005-2006. Dr. Huang has published more than 30 papers in several reputed journals. She was a member of American Diabetes Association, American Heart Association and Sigma Xi, Scientific Research Society.

Research Interest

1. Basic and translational research of stanniocalcin-1 (STC-1) as a potent anti-inflammation and anti-oxidant molecule for treating kidney and heart diseases: utilizing multiple genetically engineered mouse models such as STC-1 knock-outs, STC-1 transgenic mice, and tissue-specific STC-1 knockdown in shSTC-1 transgenic mice via ultrasound-mediated delivery of Cre recombinase.

2. Molecular actions of anti-estrogen drugs in breast cancer cells: using a variety of gene transcription assays, such as coactivator/transcriptional factor interaction assays (co-immunoprecipitation and GST-pull down), gene promoter luciferase reporter assay and chromatin-immunoprecipitation (ChIP) assay.

3. Basic and translational research of T-type Ca2+ channels in diabetes and cancers using electrophysiological approaches (e.g., Patch-Clamp), biochemical and pharmacological approaches and animal models.

4. Translational research of radiation and/or chemotherapy-induced lung inflammation and fibrosis using animal models and biochemical and histological approaches.

5. Clinical research expertise: diagnosis and treatment of pulmonary diseases using transbronchial needle aspiration and fiberoptic bronchoscopy.