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AUTHOR INFO

Krishna Doppalapudi

Section of Urologic Oncology, Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA


Articles List
Review Article Open Access

The Role of Tumor and Host Microbiome on Immunotherapy Response in Urologic Cancers

Biren Saraiya , Jake Drobner , John Pfail , Krishna Doppalapudi , Saum Ghodoussipour , Vignesh T. Packiam

The role of the microbiome in the development and treatment of genitourinary malignancies is just starting to be appreciated. Accumulating evidence suggests that the microbiome can modulate immunotherapy through signaling in the highly dynamic tumor microenvironment. Nevertheless, much is still unknown about the immuno-oncology-microbiome axis, especially in urologic oncology. The objective of this review is to synthesize our current understanding of the microbiome’s role in modulating and predicting immunotherapy response to genitourinary malignancies.

J Cancer Immunol, 2024, Volume 6, Issue 1, p1-13 | DOI: 10.33696/cancerimmunol.6.078
Co Authors
Biren Saraiya Rutgers Cancer Institute of New Jersey, Division of Medical Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA View Profile
Jake Drobner Rutgers Robert Wood Johnson Medical School, Section of Urologic Oncology, Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA View Profile
John Pfail Rutgers Robert Wood Johnson Medical School, Section of Urologic Oncology, Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA View Profile
Saum Ghodoussipour Rutgers Robert Wood Johnson Medical School, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA View Profile
Vignesh T. Packiam Rutgers Robert Wood Johnson Medical School, Section of Urologic Oncology, Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA View Profile

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