Journal of AIDS and HIV Treatment

Mini Review Open Access

CCR5 Inhibitors and HIV-1 Infection

Olga S. Latinovic, Marvin Reitz, Alonso Heredia

Cellular components are attractive targets for antiviral therapy because they do not mutate as readily as do viral proteins do [1-3]. The identification of CCR₅ as an HIV-1 coreceptor [4-7], facilitated by the discovery of the antiviral activities of CCR₅ ligand ?-chemokines [8], resulted in the development of new viral entry inhibitors to block CCR₅ binding, including both- small molecules and CCR₅ antibodies

Editorial Open Access

The Impact of Marginalization on the Continuum of Care Treatment Model on African American Communities in the Southern United States

Jill Rowe

Recently, I was asked to speak at the National Academy of Public Administration (NAPA) Conference about my experiences serving as an ethnographic consultant on the National HIV Behavioral Surveillance System (NHBS¹ ) Study. 

Editorial Open Access

Recent Progress in Preclinical HIV-1 Vaccine Research

Zizhang Sheng, Lawrence Shapiro

Since isolation in humans in 1983 [1,2], HIV-1 has developed into a global pandemic. But an effective HIV-1 vaccine has not been succeeded despite multiple human vaccine trials performed [3,4]. Challenges to an effective vaccine arise from intrinsic virological and immunological features of HIV-1 [3-8].

Case Report Open Access

Primary Lymph Node Kaposi's Sarcoma in Two HIV Positive Patients Presenting with Generalized Lymphadenopathy and Pancytopenia in a Third Level Hospital in Guatemala

Pablo Pérez Pinetta, Johanna Meléndez

We present two unique cases in which two HIV positive patients with generalized lymphadenopathy and pancytopenia without any skin lesions were diagnosed with primary lymph node Kaposi´s Sarcoma after excisional biopsy of an inguinal lymph node. 

Research Article Open Access

Anti-HIV-1 Activity of Crocodylus mindorensis (Philippine Crocodile) Serum in Cell-free and Cell-associated Virus Interactions to Human Peripheral Blood Mononuclear Cells

Hinay, Alfredo Jr A, Cadotdot, Nelyn Mae T, Tablizo, Marilou V

Highly-Active Antiretroviral Therapy (HAART) is the recommended treatment and management strategy for HIV infection. Although the existing antiretroviral drugs are indispensably significant in improving the quality and extending the lives of HIV/ AIDS individuals, the drugs still have many limitations including development of resistance, production of toxicity, and their limited availability.