Archives of Proteomics and Bioinformatics (ISSN : 2767-391X)
Scientific Archives

Ashok R. Amin

Biomedical Engineering

Virginia Tech

USA

Academic Editor

Biography

Dr. Ashok R. Amin, has been on the Faculty of the Dept. of Biomedical  Engineering at Virginia Tech. He led the Research in the Department of  Rheumatology as Director of Research and Associate Professor of  Pathology and Medicine at New York University’s Hospital for Joint  Diseases. Dr. Amin also served as the Vice President of Research at  Carilion Clinic and Advaxis Inc. He has acted as a collaborator or  consultant to 17 different pharmaceutical companies, obtained 22  patents, and authored over 90 peer-reviewed publications. Dr. Amin's  team discovered the drug ORACEATM (doxycycline, USP), which is currently being marketed by Galderma Inc.

Research Interest

  • Discovery of therapeutic targets and biomarkers, validation and development.
  • Population Genetics and Genomics of autoimmune and inflammatory diseases and cancer.
  • Structure of immunoglobulin and Ig receptor interactions and signal transduction.
  • Role of immunoglobulins and germinal centers in primary and secondary immune responses and memory.
  • Bioinformatics and biomarkers for personalized medicine in complex diseases.
  • Cellular immunology and mechanisms of inflammatory mediators in complex and infectious diseases.
  • Gene mining, bioinformatics, functional and pharmacogenomics in human osteoarthritis, rheumatoid arthritis, inflammatory diseases, cancer and infectious diseases.
  • Host-parasite interactions and mechanism of pathogenicity.
  • Regulation of ROS and mechanism of action of nitric oxide and eicosanoids.
  • Mechanisms of action of anti-inflammatory drugs and pharmacogenomics (SNP, haplotyping, proteomics and gene expression arrays) in inflammation and cancer in vitro and in vivo.
  • Pharmacological intervention and Gene Therapy.
  • Clinical research, clinical trials and tissue banking.
  • Preclinical studies on drug target /biomarker development and validation.
  • Drug testing in animal models, transgenic and knock out animals.
  • Development of diagnostics tests and small medical equipment.