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Endoscopic Ultrasound-Guided Liver Biopsy; the Pathologist’s Perspective

In this study, the safety and efficacy of liver biopsies performed by endoscopic ultrasound (EUS-LB) were compared with those performed via the traditional percutaneous route at our Medical Center between January 2018 and August 2019.

Arid5a Inroads to Immunity, Inflammation, and Cancer

The immune system is essential to host defense because it senses attacking pathogens and elicits protective immune responses. Although immune responses can protect against pathogens, uncontrolled immune responses cause tissue damage and other pathological consequences through their inflammatory mediators. 

Application of Encapsulated Probiotics in Health Care

Probiotics are generally defined as nonpathogenic living organisms that have beneficial effects on host health. The term “probiotic” means “for life” that is derived from Greek language. At first, probiotics was defined as substances that are produced with microorganisms and promote the other microorganisms.

A New Player in an Old Story: FBXO16 Prevents Breast Cancer Tumorigenesis through Disrupting Cellular Function of Nuclear β-Catenin

β-Catenin is the central modulator of the canonical Wnt signaling pathway. Upon Wnt on state, β-Catenin is translocated to the nucleus and function as a transcription coactivator for several oncogenes. In Wnt off state, β-catenin is mostly localized in the cytoplasm and sequestered by the destruction complex, the negative regulator of β-catenin expression [2,3].

Pancytopenia: An Update

Peripheral pancytopenia is not a disease by itself; rather it describes simultaneous presence of anemia, leucopenia and thrombocytopenia resulting from a number of disease processes.