Archives of Medical Case Reports

Case report is an important kind of article in medicine. The case report can be in several forms. A report might be on the new finding, new technique, rare condition or lesson learnt [1-2]. The case report on pitfall and error is interesting. It is useful for giving lesson learnt to the reader.

The Gorlin-Goltz syndrome (GGS), also referred as Nevoid Basal Cell Carcinoma Syndrome (NBCCS) or Basal Cell Nevus Syndrome (BCNS) was first described by Gorlin et al. in 1960 although it was known for decades before [1]. It is an autosomal dominant disorder characterized by KeratoCystic Odontogenic Tumors (KCOT) in the jaws,

Vulvovaginal haematoma following vagina delivery can cause a serious life-threatening complication including maternal mortality if not promptly diagnosed or properly managed yet, is no more commonly seen, especially in modern obstetric practice due to improvement in quality of care and management in labour with careful observation of mothers in labour ward following delivery.

The COVID-19 pandemic has now impacted the global population for over a year. It has been devastating for many and has challenged us all in many ways. While the advent of vaccinations looks to curtail the number of cases, multiple challenges to ending the pandemic remain, including the advent of variants, vaccine hesitancy, access to vaccines, and the impaired efficacy of vaccines in immunocompromised persons. Thus, it is still essential to continue investigating treatments for COVID-19.

Multiple myeloma (MM) manifests as neoplastic proliferation of plasma cells in the bone marrow associated with monoclonal paraprotein in the blood and/or urine, and evidence of end organ damage that can be attributed to the underlying plasma cell proliferative disorder. The median age at diagnosis of multiple myeloma is 70 years, and the incidence increases with age.

Chronic Lymphocytic Leukemia (CLL) is a mature B cell neoplasm characterized by a progressive accumulation of monoclonal B lymphocytes. It manifests primarily in the blood. Infiltration of CLL lymphocytes outside of this site is relatively rare and is defined as extra medullary CLL.

The MYCN oncoprotein has been notoriously undruggable and is infamous for causing aggressive cancer with poor outcomes in children and adults. Following surgery, radiation, and chemotherapy, patients who develop progressive disease have few treatment options. An analysis of the dysregulated protein network caused by MYCN amplification suggested co-targeting PLK1, AURKA, CKS1, AKT, MTOR, and USP7 would be useful to take advantage of synthetic lethal vulnerabilities

Ischemic optic neuropathies are prevalent diseases and important cases of vision loss. In particular, non arteritic ischemic optic neuropathy (NAION) is the most common cause of optic neuropathy after 50 years of age and the etiology of NAION involves risk factors from the patients and some drugs as triggers, like triptans, selective agonists of 5-HT1 receptors.

Objective: To describe the evolution of Utero-Vesical Fistula (UVF) of one patient who received conservative treatment using intravenous (IV) infusion of 120x106 Adipose tissue Mesenchymal Stem Cells (ADMSCs). Clinical case report: A 36-year-old female presented with postcesarean hematuria 3 hours after an emergency c-section was performed consequently to placental abruption during labor.

We described a 15-year-old- a boy who presented with neurofibromatosis type 1 and Crohn’s disease. Neurofibromatosis 1 (NF1) is the most common form of NF, affecting 1 in 3000 individuals. Crohn’s disease is one of the inflammatory bowel diseases. Its incidence is significantly rising in Ireland. Concomitant association of NF1 and Crohn’s disease is a rare finding. This is the first case reported in the paediatric population.

Purpose: To describe the diagnosis and management of enterocele with high risk of bowel ischemia in patients with pelvic organ prolapse. Methods: We describe the clinical case of an 81-year-old patient, hypertensive, obese, anticoagulated because of an atrial fibrillation and pelvic organ prolapse. Initially, conservative treatment was offered due to the high surgical risk, but sometime later the patient came to the emergency department with enterocele and risk of intestinal ischemia.

Trichomonas vaginalis is a common cause of symptomatic vaginitis in women. Trichomoniasis occurs more frequently in people with multiple sexual partners. Women often present with vaginal discharge, painful intercourse, urinary tract infection symptoms, vaginal itching, or pelvic pain. The strawberry cervix is a finding upon physical examination where the cervix has an erythematous, punctate, and papilliform appearance.

Ulnar impingement syndrome is caused by a shortened ulna impinging on the distal radius and causing a painful, disabling pseudoarthrosis. Vaughan-Jackson syndrome is characterized by a disruption of the digital extensor tendons, beginning on the ulnar side with the extensor digiti minimi (EDM) and extensor digitorum communis (EDC) tendon of the small finger.

Ptosis or the dropping of an eyelid can affect both the adult and pediatric populations and can be caused by various factors. Ptosis is not very common and in children, the common causes include orbital cellulitis, congenital ptosis, Cranial Nerve III palsy, and Horner’s syndrome.

Posterior quadrant epilepsy is relatively uncommon and refractory seizures from these regions are difficult to diagnose and manage. A 28-year-old woman presented for evaluation of her seizures. Scalp Electroencephalogram (EEG) showed seizures with independent onset over the right posterior and left anterior regions.

The COVID-19 virus with severe acute respiratory syndrome (SARS) has a remarkable effect on morbidity and mortality. Non-ST elevation myocardial infarction (NSTEMI) is a category of acute coronary syndrome (ACS) that may represent a primary cardiac manifestation of COVID-19 disease. The QRS-complex fragmentation had been considered a hallmark of structural heart disease. Wavy triple, an electrocardiographic sign (Yasser’s sign) is a new specific diagnostic sign and therapeutic guide for hypocalcemia.

Idiopathic normal pressure hydrocephalus (iNPH) is a special type of hydrocephalus that is characterized by cognitive decline, gait disturbance, and urinary incontinence. It can lead to dementia and bedridden within 1-3 years. Without surgical treatment in time, the prognosis was bleak. We report an iNPH case misdiagnosed with Alzheimer’s disease, with a disease course of 3 years.

This case report presents the clinical details, diagnostic findings, and management of a 64-year-old female patient who suffered a tibia and fibula fracture, presented in an atypical manner, after twisting her ankle during daily activities. The medical background, physical examination, radiological results, and course of treatment of the patient are detailed.

Background: Cancer is the second leading cause of mortality after cardiovascular disease. The second common leading cause of mortality in cancer patients is thrombosis, vary from arterial or venous thromboembolism to disseminated intravascular coagulation.

Purulent pericarditis was a prevalent complication of streptococcal pneumonia prior to the antibiotic era. In this article, we report a 68-yearold male presenting with dyspnea, chest pain, left knee pain, diagnosed with S. pneumoniae bacteremia and septic arthritis with isolation of same pathogen from synovial fluid.